01
Import
Load CSV or Excel plate-reader data
Dose-response and relative-potency assay software
Analyze potency assays from plate-reader data to the final report.
Import CSV or Excel data, define the plate layout and dilution series, fit linear, 4PL, or 5PL models, evaluate suitability criteria, and generate a PDF with the settings, results, and exclusions.
CSV and Excel imports Linear, 4PL, and 5PL models Exclusion reasons Settings saved with results PDF reports
ANALYSIS / EXAMPLE-04Relative potency · 4PL
restricted fitRelative potency80.0%within configured range
Slope ratio1.00criterion passed
DispositionPassedall configured checks
Dose–response fitReference Test
All configured suitability checks passed
Included with the resultSource data + analysis configuration fingerprints
AnalysisPlate import through PDF reportSource data and analysis configuration fingerprintsTeam workflowsMethod and report approvals, run history, and trending
One assay workflow
From raw measurements to a finished report.
Import the reader file, define the plate and dilution series, fit the response model, assess suitability, document exclusions, and generate the PDF without rebuilding the analysis in another tool.
02
Map
Assign samples, references, and replicates
03
Dilute
Calculate concentrations from the series
04
Fit
Run linear, 4PL, or 5PL models
05
Evaluate
Apply configured suitability criteria
06
Inspect
Review curves, parameters, and exclusions
07
Report
Generate the complete formatted PDF
Why the workflow matters
A fitted curve does not show how the result was produced.
Potency teams often have to reconstruct which settings were used, how wells mapped to samples, why a value was excluded, and which report belongs with the source file. Provenarium keeps those details with each run.
Files and settings end up in different places
Reader files, plate maps, dilution calculations, and model settings are easy to separate when an analysis spans several tools.
Reviewers cannot see how the result was calculated
A curve and summary value do not explain the sample assignments, exclusions, suitability criteria, or model settings.
Report preparation adds manual steps
Analysts copy values and plots into another document instead of generating the PDF directly from the analysis results.
Organization workspace
Use the approved assay method for every run.
Save the plate layout, dilution scheme, model settings, suitability criteria, and report format as a versioned method. Analysts select an approved version, and reviewers can see what changed and why.
01Draft
02In review
03Approved
04Routine
05Superseded
06Retired
Saved assay methodVersion 3 · Approved
Relative potency · 4PL
Version history3 revisionsMethod ownerBioassay teamStatusApproved for routine use
Revision historySee each change, its reason, verification result, approver, and effective date.
Analysis and review
Review each run and compare assay performance over time.
Inspect curves, parameters, suitability results, and exclusions for an individual run. Organization workspaces add run history for examining drift, comparing lots, and following up on exceptions.
4PL / restricted fit
Fit the model and calculate potency
Each run records the plate map, model settings, exclusions, suitability criteria, results, and report settings.
Fit criterion Passed Slope ratio Passed Replicate CV Passed
Review suitability and exclusions
Check observed values, fitted parameters, suitability results, exclusion reasons, and the generated PDF.
Released runsLast 8 runs
Monitor assay performance
Use control charts, drift signals, lot comparisons, and alerts to review performance across completed runs.
For regulated bioassay teams
Manage assay methods and results within your quality system.
Every analysis records the software version, SHA-256 fingerprints for the source data file and analysis configuration, exclusion reasons, analyst, date, and report details. The Team plan adds approved methods, role-based access, change history, reviewer approval and electronic signatures tied to a specific report version, product requirements, software test records, and qualification protocol templates. Your organization validates its configured workflow for its intended use.
See what Provenarium provides for validationINCLUDED WITH EACH ANALYSISRecords needed to review the result
Recorded software version Source data and analysis configuration fingerprints Required exclusion reasons Analyst, date, and run details
Validation is specific to your useYour organization defines intended use, approves procedures, trains users, and validates its configured workflow.
Ways to use Provenarium
Choose a free individual workspace, a shared Team workspace, or custom development.
The Team plan adds approved methods, report review and electronic signatures tied to each report version, protected run history, product requirements and software test records, and qualification protocol templates. Custom work covers assay-specific calculations, importers, reports, integrations, migration, and customer-specific implementation.
Individual
Run a complete relative-potency analysis in a private workspace, free.
- Personal workspace
- CSV and Excel plate import
- Linear, 4PL, and 5PL fitting
- Analysis settings and PDF export
Team
Manage approved assay methods, report review and signing, and protected run records across your bioassay team.
- Shared organization workspace and run history
- Configurable methods and report templates
- Reviewer approval and electronic signatures tied to each report version
- Protected run records and change history
- Regulated-workflow package with product requirements, software test records, and qualification protocol templates
Consulting + custom development
Add assay-specific calculations, file imports, reports, integrations, migration, or implementation support beyond the Team plan.
- Custom assay models and calculations
- Assay-specific import and analysis workflows
- Custom reports and data-exchange formats
- Plate-reader, LIMS, ELN, and other system integrations
- Customer-specific data migration, implementation, and validation support
Free demo
Run the 4PL example from CSV through the finished PDF report.
Define the plate layout and dilution series, fit the curves, evaluate suitability, and inspect the final report—or tell us how your method differs.